{"id":25001,"date":"2025-08-08T16:49:13","date_gmt":"2025-08-08T08:49:13","guid":{"rendered":"https:\/\/aicats.wiki\/?p=25001"},"modified":"2025-08-08T16:49:43","modified_gmt":"2025-08-08T08:49:43","slug":"genie3%e8%a9%b3%e8%a7%a3%ef%bc%9a%e5%9f%ba%e5%9b%a0%e8%aa%bf%e6%8e%a7%e7%b6%b2%e7%b5%a1%e9%87%8d%e5%bb%ba%e7%9a%84%e5%bc%b7%e5%a4%a7ai%e5%b7%a5%e5%85%b7%e5%8f%8a%e5%85%b6%e6%87%89%e7%94%a8%e5%a0%b4","status":"publish","type":"post","link":"https:\/\/aicats.wiki\/tw\/2025\/08\/08\/25001-html","title":{"rendered":"Genie3\u8a73\u89e3\uff1a\u57fa\u56e0\u8abf\u63a7\u7db2\u8def\u91cd\u5efa\u7684\u5f37\u5927AI\u5de5\u5177\u53ca\u5176\u61c9\u7528\u60c5\u5883\u89e3\u6790"},"content":{"rendered":"<p><strong>Genie3\u662f\u76ee\u524d\u57fa\u56e0\u8abf\u63a7\u7db2\u7d61\u91cd\u5efa\u9818\u57df\u6700\u53d7\u63a8\u5d07\u7684<a href=\"https:\/\/aicats.wiki\/tw\/2025\/07\/26\/19749-html\/\" title=\"bolt \u4e2d\u6587\u8a73\u89e3\uff1a\u570b\u5167\u7528\u6236\u5982\u4f55\u6709\u6548\u7387\u4f7f\u7528Bolt AI\u5de5\u5177\uff1f\">AI\u5de5\u5177<\/a>\u4e4b\u4e00\uff0c\u4f9d\u9760\u6574\u5408\u5b78\u7fd2\uff08\u5982\u96a8\u6a5f\u68ee\u6797\uff09\u6f14\u7b97\u6cd5\uff0c\u80fd\u9ad8\u6548\u6316\u6398\u57fa\u56e0\u9593\u8907\u96dc\u8abf\u63a7\u95dc\u4fc2\u3002\u672c\u6587\u8a73\u7d30\u8aaa\u660e\u4e86Genie3\u7684\u6280\u8853\u539f\u7406\u3001\u4f7f\u7528\u65b9\u6cd5\u3001\u512a\u52e2\u6027\u80fd\u53ca\u5176\u5728\u75be\u75c5\u7814\u7a76\u3001\u55ae\u7d30\u80de\u7d44\u5b78\u3001\u5408\u6210\u751f\u7269\u7b49\u9ad8\u7aef\u524d\u6cbf\u9818\u57df\u7684\u5ee3\u6cdb\u61c9\u7528\u5834\u666f\u3002\u5c0d\u65bc\u5f9e\u4e8b\u57fa\u56e0\u8868\u73fe\u8cc7\u6599\u6df1\u5ea6\u6316\u6398\u7684\u79d1\u5b78\u7814\u7a76\u4eba\u54e1\u800c\u8a00\uff0cGenie3\u662f\u4e0d\u53ef\u591a\u5f97\u7684\u751f\u4fe1\u5229\u5668\u3002<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/aicats.wiki\/wp-content\/uploads\/2025\/08\/my_prefix_1754620337.png\" alt=\"Genie3\u8a73\u89e3\uff1a\u57fa\u56e0\u8abf\u63a7\u7db2\u8def\u91cd\u5efa\u7684\u5f37\u5927AI\u5de5\u5177\u53ca\u5176\u61c9\u7528\u60c5\u5883\u89e3\u6790\" class=\"wp-image-51824\"\/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Genie3\u8be6\u89e3\uff1a\u57fa\u56e0\u8c03\u63a7\u7f51\u7edc\u91cd\u5efa\u7684\u5f3a\u5927<a class=\"external\" href=\"https:\/\/aicats.wiki\/tw\/tag\/ai\" title=\"\u67e5\u770b\u8207 AI \u76f8\u95dc\u7684\u6587\u7ae0\" target=\"_blank\">AI<\/a>\u5de5\u5177\u53ca\u5176\u5e94\u7528\u573a\u666f\u89e3\u6790<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Genie3\u7c21\u4ecb\u8207\u6280\u8853\u539f\u7406<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u4ec0\u9ebc\u662fGenie3\uff1f<\/h3>\n\n\n\n<p><strong>Genie3\u662f\u4e00\u7a2e\u57fa\u65bc\u4eba\u5de5\u667a\u6167\u7684\u57fa\u56e0\u8abf\u63a7\u7db2\u7d61\uff08Gene Regulatory Network, GRN\uff09\u63a8\u8ad6\u5de5\u5177<\/strong>\uff0c\u7531\u6cd5\u570bINRIA\u7814\u7a76\u6240\u958b\u767c\uff0c\u6191\u85c9\u5176\u5353\u8d8a\u7684\u7279\u5fb5\u9078\u64c7\u6a5f\u5236\u8207\u6cdb\u5316\u6027\u80fd\uff0c\u5728\u57fa\u56e0\u8868\u73fe\u6578\u64da\u9a45\u52d5\u7684\u7db2\u8def\u91cd\u5efa\u9818\u57df\u4e2d\u812b\u7a4e\u800c\u51fa\u3002 Genie3\u80fd\u5920\u5229\u7528\u9ad8\u901a\u91cf\u8f49\u9304\u7d44\u6578\u64da\uff0c\u63ed\u793a\u57fa\u56e0\u9593\u6f5b\u5728\u8abf\u63a7\u95dc\u4fc2\uff0c\u70ba\u751f\u547d\u8907\u96dc\u8abf\u63a7\u6a5f\u5236\u3001\u75be\u75c5\u5206\u5b50\u6a19\u8a18\u53ca\u5408\u6210\u751f\u7269\u7814\u7a76\u7b49\u63d0\u4f9b\u4e86\u5805\u5be6\u7684\u6578\u64da\u57fa\u790e\u3002<\/p>\n\n\n\n<p>\u5176\u512a\u52e2\u9084\u5728\u65bc<strong>\u9748\u6d3b\u8cc7\u6599\u8f38\u5165\u3001\u5275\u65b0AI\u6f14\u7b97\u6cd5\uff08\u5c24\u5176\u662f\u96a8\u6a5f\u68ee\u6797\u8207\u6975\u7aef\u96a8\u6a5f\u6a39\uff09\u652f\u6301<\/strong>\uff0c\u4ee5\u53ca\u570b\u969b\u77e5\u540d\u6b0a\u5a01\u6a5f\u69cb\uff08\u5982Nature Methods\u5927\u578b\u8a55\u6e2c\uff09\u7684\u4e00\u81f4\u597d\u8a55\u3002<\/p>\n\n\n\n<p>\u76f8\u95dc\u8cc7\u6e90\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5b98\u65b9\u7db2\u7ad9\u8207\u6307\u5357\uff1a<a href=\"https:\/\/bioconductor.org\/packages\/release\/bioc\/html\/GENIE3.html\" target=\"_blank\"  rel=\"nofollow noopener\"  class=\"external\" >Genie3 Bioconductor\u9801\u9762<\/a><\/li>\n\n\n\n<li>\u5b78\u8853\u539f\u6587\uff1a<a href=\"https:\/\/www.nature.com\/articles\/nmeth.4463\" target=\"_blank\"  rel=\"nofollow noopener\"  class=\"external\" >Nature Methods\u8ad6\u6587<\/a><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Genie3\u7684\u6838\u5fc3\u6280\u8853\u2014\u6574\u5408\u5b78\u7fd2<\/h3>\n\n\n\n<p><strong>Genie3\u6838\u5fc3\u6e90\u81ea\u65bc\u6574\u5408\u5b78\u7fd2\u6f14\u7b97\u6cd5\uff08\u96a8\u6a5f\u68ee\u6797\u3001\u6975\u7aef\u96a8\u6a5f\u6a39\uff09\uff0c\u7528\u65bc\u57fa\u65bc\u57fa\u56e0\u8868\u73fe\u9810\u6e2c\u7684\u8ff4\u6b78\u6a21\u578b\uff1a<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u70ba\u6bcf\u500b\u57fa\u56e0\u5efa\u7acb\u7368\u7acb\u591a\u8b8a\u91cf\u8ff4\u6b78\u6a21\u578b<\/li>\n\n\n\n<li>\u5c07\u5176\u4ed6\u57fa\u56e0\uff08\u7279\u5225\u662f\u5019\u9078\u8abf\u63a7\u56e0\u5b50\uff09\u7684\u8868\u73fe\u91cf\u4f5c\u70ba\u7279\u5fb5\u8f38\u5165\uff0c\u76ee\u6a19\u57fa\u56e0\u8868\u73fe\u70ba\u8f38\u51fa<\/li>\n\n\n\n<li><strong>\u7d9c\u5408\u5404\u7279\u8cea\u7684\u91cd\u8981\u6027\u5f97\u5206\uff0c\u91cf\u5316\u8abf\u63a7\u95dc\u4fc2\u5f37\u5f31<\/strong><\/li>\n\n\n\n<li>\u6240\u6709\u9810\u6e2c\u6a21\u578b\u7684\u8a08\u7b97\u7d50\u679c\u6574\u5408\u70ba\u52a0\u6b0a\u7db2\u8def\u77e9\u9663\uff0c\u53cd\u6620\u5168\u90e8\u57fa\u56e0\u8abf\u63a7\u6b0a\u91cd<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1593\" height=\"921\" src=\"https:\/\/aicats.wiki\/wp-content\/uploads\/2025\/08\/image-311.png\" alt=\"Genie3 Bioconductor\u9801\u9762\" class=\"wp-image-25253\"\/><figcaption class=\"wp-element-caption\">\u5716\uff0f<a href=\"https:\/\/bioconductor.org\/packages\/release\/bioc\/html\/GENIE3.html\" target=\"_blank\"  rel=\"nofollow noopener\"  class=\"external\" >Genie3 Bioconductor\u9801\u9762<\/a><\/figcaption><\/figure>\n\n\n\n<p><strong>\u6f14\u7b97\u6cd5\u6d41\u7a0b\u7c21\u660e\u6458\u8981\uff1a<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><th>\u6b65\u9a5f<\/th><th>\u63cf\u8ff0<\/th><\/tr><tr><td>\u6578\u64da\u5c0e\u5165<\/td><td>\u8b80\u53d6\u6a19\u6e96\u5316\u7684\u8868\u9054\u77e9\u9663\uff08\u884c\uff1a\u57fa\u56e0\uff0c\u5217\uff1a\u6a23\u672c\uff09<\/td><\/tr><tr><td>\u5019\u9078\u96c6\u5b9a\u7fa9<\/td><td>\u9078\u5b9a\u8f49\u9304\u56e0\u5b50\/\u8abf\u63a7\u56e0\u5b50\u5217\u8868<\/td><\/tr><tr><td>\u6a21\u578b\u8a13\u7df4<\/td><td>\u6bcf\u500b\u57fa\u56e0\u7368\u7acb\u56de\u6b78\uff0c\u8f38\u5165\u70ba\u5176\u5b83\u57fa\u56e0\u8868\u9054<\/td><\/tr><tr><td>\u91cd\u8981\u6027\u6392\u5e8f<\/td><td>\u7d71\u8a08\u7279\u5fb5\u91cd\u8981\u6027\uff0c\u91cf\u5316\u8abf\u7bc0\u9ede\u5f71\u97ff<\/td><\/tr><tr><td>\u532f\u51fa\u7d50\u679c<\/td><td>\u8f38\u51fa\u57fa\u56e0\u5c0d\u8207\u6b0a\u91cd\uff0c\u5f8c\u7528\u65bc\u7db2\u8def\u8996\u89ba\u5316\u5206\u6790<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">Genie3\u7684\u512a\u52e2\u8207\u6027\u80fd<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u975e\u53c3\u6578\u9069\u61c9\u8907\u96dc\u751f\u7269\u6578\u64da<\/strong><\/li>\n\n\n\n<li><strong>\u9b6f\u68d2\u6027\u5f37\uff0c\u5c0d\u566a\u97f3\u8207\u5197\u9918\u6297\u6027\u597d<\/strong><\/li>\n\n\n\n<li>\u652f\u6301\u591a\u7d44\u5b78\u6a23\u672c\u548c\u55ae\u7d30\u80de\u985e\u578b\u5206\u6790<\/li>\n\n\n\n<li>\u5206\u6790\u6d41\u7a0b\u81ea\u52d5\u5316\uff0c\u8a2d\u5b9a\u7c21\u55ae<\/li>\n\n\n\n<li><strong>\u5728DREAM5\u570b\u969b\u7af6\u8cfd\u4e2d\u8a55\u70ba\u9802\u5c16\u6f14\u7b97\u6cd5\u4e4b\u4e00<\/strong><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Genie3\u7684\u4f7f\u7528\u65b9\u6cd5\u53ca\u8cc7\u6599\u6d41\u7a0b<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u8cc7\u6599\u6e96\u5099\u53ca\u8f38\u5165\u683c\u5f0f<\/h3>\n\n\n\n<p><strong>Genie3\u7684\u8cc7\u6599\u9700\u6c42\uff1a<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u884c\u70ba\u57fa\u56e0\uff08Gene\uff09\uff0c\u5217\u70ba\u6a23\u672c\uff08Sample\uff09<\/li>\n\n\n\n<li>\u55ae\u5143\u683c\u70ba\u8868\u9054\u91cf\uff08\u5982\u8a08\u6578\u3001TPM\u3001FPKM\u3001RPKM\u3001log\u8f49\u63db\u503c\u7b49\uff09<\/li>\n\n\n\n<li>\u9069\u5408Bulk RNA-Seq\u3001Microarray\u3001Single-cell RNA-Seq\u7b49\u4e3b\u6d41\u751f\u4fe1\u6578\u64da<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"1593\" height=\"921\" src=\"https:\/\/aicats.wiki\/wp-content\/uploads\/2025\/08\/image-312.png\" alt=\"\u5b89\u88dd\u6307\u5f15\" class=\"wp-image-25258\"\/><figcaption class=\"wp-element-caption\">\u5716\uff0f\u5b89\u88dd\u6307\u5f15<\/figcaption><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">\u5b89\u88dd\u8207\u4f7f\u7528\u65b9\u6cd5<\/h3>\n\n\n\n<p><strong>Genie3\u4e3b\u8981\u65bcR\/Bioconductor\u5b89\u88dd\uff1a<\/strong><\/p>\n\n\n\n<!--wp-compress-html--><!--wp-compress-html no compression-->\n<pre class=\"wp-block-code\"><code>if (!requireNamespace(&quot;BiocManager&quot;, quietly=TRUE)) install.packages(&quot;BiocManager&quot;) BiocManager::install(&quot;GENIE3&quot;)\n<\/code><\/pre>\n<!--wp-compress-html no compression--><!--wp-compress-html-->\n\n\n\n<p>\u57fa\u672c\u547c\u53eb\u6b65\u9a5f\uff1a<\/p>\n\n\n\n<!--wp-compress-html--><!--wp-compress-html no compression-->\n<pre class=\"wp-block-code\"><code>library(GENIE3) # \u5efa\u69cb\u8868\u9054\u77e9\u9663exprMatr &lt;- matrix(sample(1:10, 100, replace=TRUE), nrow=20) rownames(exprMatr) &lt;- paste(&quot;Gene&quot;, 1:20, sep=&quot;&quot;) # \u6307\u5b9a\u5019\u9078\u8abf\u7bc0\u56e0\u5b50regulators &lt;- c(&quot;Gene2&quot;, &quot;Gene4&quot;, &quot;Gene7&quot;) # \u904b\u884cGenie3\u63a8\u65b7\u7db2\u7d61weightMat &lt;- GENIE3(exprMatr, regulators=regulators, treeMethod=&quot;ET&quot;, K=7, nTreesList=7, 15050 \u8868\u683c\u7372\u53d6\u8868 507, nTree 107, nTree 10) 153850) 1585475), nT\n<\/code><\/pre>\n<!--wp-compress-html no compression--><!--wp-compress-html-->\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/aicats.wiki\/wp-content\/uploads\/2025\/08\/my_prefix_1754620342.png\" alt=\"Genie3 R\u7a0b\u5f0f\u78bc\u904b\u884c\u4ecb\u9762\" class=\"wp-image-51824\"\/><figcaption class=\"wp-element-caption\">\u5716\uff0fGenie3 R\u7a0b\u5f0f\u78bc\u904b\u884c\u4ecb\u9762<\/figcaption><\/figure>\n\n\n\n<p><strong>\u4e3b\u8981\u53c3\u6578\u7e3d\u7d50\uff1a<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><th>\u53c3\u6578<\/th><th>\u8aaa\u660e<\/th><th>\u5e38\u898b\u9078\u64c7<\/th><\/tr><tr><td>exprMatrix<\/td><td>\u8f38\u5165\u8868\u9054\u77e9\u9663<\/td><td>\u5fc5\u9808<\/td><\/tr><tr><td>regulators<\/td><td>\u5019\u9078\u8abf\u63a7\u56e0\u57fa\u56e0\u540d<\/td><td>\u5efa\u8b70\u8f49\u9304\u56e0\u5b50\u5217\u8868<\/td><\/tr><tr><td>treeMethod<\/td><td>\u6a39\u6a21\u578b\u985e\u578b<\/td><td>\u201cRF\u201d\/\u201cET\u201d<\/td><\/tr><tr><td>nTrees<\/td><td>\u68ee\u6797\u6a39\u6578\u91cf<\/td><td>50~1000<\/td><\/tr><tr><td>K<\/td><td>\u6bcf\u6b21\u5206\u5272\u7279\u5fb5\u6578<\/td><td>\u9810\u8a2d\u221aN<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">\u7d50\u679c\u89e3\u8b80\u8207\u7db2\u8def\u8f38\u51fa<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u8f38\u51fa\u70ba\u52a0\u6b0a\u9130\u63a5\u77e9\u9663\uff0c\u6bcf\u884c\u5c0d\u61c9\u76ee\u6a19\u57fa\u56e0\u3001\u5217\u70ba\u8abf\u63a7\u56e0\u5b50\uff0c\u6578\u503c\u4ee3\u8868\u8abf\u63a7\u5f37\u5ea6<\/strong><\/li>\n\n\n\n<li>\u53ef\u900f\u904e<code>getLinkList()<\/code>\u53d6\u5f97\u300c\u8abf\u7bc0\u56e0\u5b50-\u6a19\u9776\u57fa\u56e0-\u6b0a\u91cd\u300d\u4e09\u5143\u7d44\uff0c\u4fbf\u65bc\u5f8c\u7e8c\u6392\u5e8f\u8207\u8996\u89ba\u5316\u5206\u6790<\/li>\n\n\n\n<li><strong>\u53ef\u91dd\u5c0d\u5be6\u969b\u9700\u6c42\u7be9\u9078Top\u8abf\u63a7\u95dc\u4fc2\u7528\u65bc\u5bcc\u96c6\u6316\u6398<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u7bc4\u4f8b\u8f38\u51fa\uff1a<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><th>\u8abf\u63a7\u56e0\u5b50<\/th><th>\u76ee\u6a19\u57fa\u56e0<\/th><th>\u6b0a\u91cd<\/th><\/tr><tr><td>Gene2<\/td><td>Gene5<\/td><td>0.2111<\/td><\/tr><tr><td>Gene4<\/td><td>Gene19<\/td><td>0.1902<\/td><\/tr><tr><td>Gene7<\/td><td>Gene13<\/td><td>0.1709<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/aicats.wiki\/wp-content\/uploads\/2025\/08\/my_prefix_1754620349.png\" alt=\"\u57fa\u56e0\u8abf\u63a7\u7db2\u7d61\u7d50\u679c\u8868\" class=\"wp-image-51824\"\/><figcaption class=\"wp-element-caption\">\u5716\uff0f\u57fa\u56e0\u8abf\u63a7\u7db2\u7d61\u7d50\u679c\u8868<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Genie3\u61c9\u7528\u5834\u666f\u89e3\u6790<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u75be\u75c5\u751f\u7269\u6a19\u8a18\u8207\u8907\u96dc\u75be\u75c5\u767c\u75c5\u6a5f\u5236\u7814\u7a76<\/h3>\n\n\n\n<p><strong>Genie3\u5ee3\u6cdb\u7528\u65bc\u764c\u75c7\u3001\u514d\u75ab\u6027\u75be\u75c5\u3001\u7f55\u898b\u75be\u75c5\u7684\u8abf\u63a7\u7db2\u7d61\u89e3\u6790<\/strong>\uff0c\u53ef\u900f\u904e\u60a3\u8005\u8207\u5c0d\u7167\u6a23\u672c\u8cc7\u6599\u63a2\u52d8\u95dc\u9375\u8abf\u63a7\u56e0\u5b50\uff0c\u7e6a\u88fd\u75c5\u7406\u7db2\u7d61\uff0c\u63ed\u793a\u7570\u5e38\u8868\u73fe\u80cc\u5f8c\u7684\u8abf\u63a7\u6839\u6e90\u3002\u76f8\u95dc\u9818\u57df\u5982\u4eba\u985e\u57fa\u56e0\u7d44\u7db2\u7d61\u91cd\u5efa\u3001\u4e73\u764c\u8f49\u9304\u56e0\u5b50\u7be9\u6aa2\u7b49\u5747\u7a4d\u6975\u63a1\u7528Genie3\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u55ae\u7d30\u80deRNA\u5b9a\u5e8f\u8207\u7570\u8cea\u6027\u5206\u6790<\/h3>\n\n\n\n<p>\u5728\u55ae\u7d30\u80de\u8f49\u9304\u7d44\uff08scRNA-seq\uff09\u76db\u884c\u7684\u8da8\u52e2\u4e0b\uff0c<strong>Genie3\u884d\u751f\u51fa\u5c08\u70ba\u55ae\u7d30\u80de\u8cc7\u6599\u8a2d\u8a08\u7684\u5206\u6790\u67b6\u69cb\uff08\u5982SCENIC\uff09<\/strong>\uff0c\u5be6\u73fe\u7d30\u80de\u72c0\u614b\u7279\u7570\u8abf\u63a7\u6a21\u7d44\u8207\u4e9e\u7fa4\u7570\u8cea\u6027\u5206\u6790\u3002<\/p>\n\n\n\n<p>SCENIC\u6d41\u7a0b\u7c21\u8868\uff1a<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><th>\u6b65\u9a5f<\/th><th>Genie3\u4f5c\u7528<\/th><th>\u4e0b\u6e38\u5206\u6790<\/th><\/tr><tr><td>Co-expression<\/td><td>\u63a2\u6e2c\u8abf\u63a7\u5c0d<\/td><td>RcisTarget<\/td><\/tr><tr><td>Motif Enrichment<\/td><td>\u5f97\u5206\u7be9\u9078<\/td><td>AUCell<\/td><\/tr><tr><td>Module Building<\/td><td>\u5efa\u7acb\u4e9e\u7fa4\u7db2\u7d61<\/td><td>Cytoscape\u7b49\u53ef\u8996\u5316<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/aicats.wiki\/wp-content\/uploads\/2025\/08\/my_prefix_1754620352.png\" alt=\"\u5408\u6210\u751f\u7269\u5b78\u57fa\u56e0\u7db2\u7d61\" class=\"wp-image-51824\"\/><figcaption class=\"wp-element-caption\">\u5716\uff0f\u5408\u6210\u751f\u7269\u5b78\u57fa\u56e0\u7db2\u7d61<\/figcaption><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">\u5408\u6210\u751f\u7269\u8207\u529f\u80fd\u57fa\u56e0\u7d44\u5de5\u7a0b<\/h3>\n\n\n\n<p><strong>\u5728\u5fae\u751f\u7269\u57fa\u56e0\u5de5\u7a0b\u8207\u5408\u6210\u7db2\u8def\u8a2d\u8a08\u9818\u57df\uff0cGenie3\u53ef\u9006\u63a8\u51fa\u81ea\u7136\u7cfb\u7d71\u8abf\u63a7\u908f\u8f2f<\/strong>\uff0c\u70ba\u4eba\u5de5\u74b0\u8def\u8a2d\u8a08\u548c\u8abf\u63a7\u6a21\u7d44\u512a\u5316\u63d0\u4f9b\u5ca9\u5be6\u7684\u6578\u64da\u652f\u63f4\u3002\u5e38\u898b\u65bc\u5927\u8178\u687f\u83cc\u3001\u9175\u6bcd\u83cc\u3001\u690d\u7269\u7b49\u6a21\u5f0f\u751f\u7269\u7cfb\u7d71\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u7db2\u8def\u8996\u89ba\u5316\u8207\u751f\u4fe1\u96c6\u6210<\/h3>\n\n\n\n<p>Genie3\u532f\u51fa\u7684\u52a0\u6b0a\u9130\u63a5\u8868\u683c\u53ef\u76f4\u63a5\u532f\u5165Cytoscape\u3001Gephi\u7b49\u4e3b\u6d41\u5e73\u53f0\uff0c\u9023\u52d5\u8f49\u9304\u56e0\u5b50\u8cc7\u6599\u5eab\uff08TRRUST\u3001TRANSFAC\uff09\u8207\u5bcc\u96c6\u5206\u6790\uff0c\u652f\u63f4\u7aef\u5c0d\u7aef\u7684\u8cc7\u6599\u63a2\u52d8\u9023\u7d50\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">AI\u5206\u6790\u6574\u5408\u7684\u524d\u6cbf\u61c9\u7528<\/h3>\n\n\n\n<p><strong>Genie3\u9ad8\u5ea6\u76f8\u5bb9\u4e3b\u6d41\u751f\u4fe1\u5206\u6790\u5e73\u53f0\uff08scanpy, Seurat, WGCNA\uff09\uff0c\u53ef\u90e8\u7f72\u65bc\u96f2\u7aef\u904b\u7b97\u8207\u9ad8\u6548\u80fd\u904b\u7b97\u7ba1\u9053<\/strong>\u3002\u6210\u70ba\u764c\u75c7\u6f14\u5316\u3001\u85e5\u7269\u53cd\u61c9\u9810\u6e2c\u3001\u7d44\u5b78\u806f\u5408\u8cc7\u6599\u5efa\u6a21\u7b49\u591a\u9818\u57df\u7db2\u8def\u5206\u6790\u91cd\u8981\u5f15\u64ce\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Genie3\u6bd4\u8f03\u5176\u4ed6\u7db2\u8def\u5206\u6790\u5de5\u5177<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><th>\u5de5\u5177\u540d\u7a31<\/th><th>\u6f14\u7b97\u6cd5\u539f\u7406<\/th><th>\u7279\u9ede<\/th><th>\u7f3a\u9ede<\/th><\/tr><tr><td>Genie3<\/td><td>\u96a8\u6a5f\u68ee\u6797\u8ff4\u6b78<\/td><td>\u5b9a\u91cf\u8abf\u63a7\u5f37\u5ea6\u3001\u6297\u566a\u512a\u7570<\/td><td>\u8017\u6642\u8f03\u9577\uff0c\u9700\u9ad8\u5167\u5b58<\/td><\/tr><tr><td>ARACNE<\/td><td>\u4e92\u4fe1\u606f\uff0c\u964d\u566a\u526a\u679d<\/td><td>\u7d93\u5178\uff0c\u9069\u5408\u5927\u898f\u6a21\u7be9\u9078<\/td><td>\u4e8c\u5143\u8f38\u51fa\uff0c\u53c3\u6578\u591a<\/td><\/tr><tr><td>WGCNA<\/td><td>\u52a0\u6b0a\u76f8\u95dc\u6027\u7db2\u7d61<\/td><td>\u6a21\u7d44\u6aa2\u6e2c\u597d\uff0c\u9069\u5408\u5927\u6a23\u672c<\/td><td>\u7121\u5b9a\u5411\u8abf\u63a7\uff0c\u96f6\u5faa\u56e0\u679c<\/td><\/tr><tr><td>CLR<\/td><td>\u4e92\u8cc7\u8a0az-score<\/td><td>\u7121\u76e3\u7763\uff0c\u6f14\u7b97\u6cd5\u5feb<\/td><td>\u8abf\u63a7\u65b9\u5411\u5340\u5206\u5f31<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>Genie3\u56e0\u5f37\u5927\u7684\u5b9a\u91cf\u8abf\u63a7\u63a8\u8ad6\u548c\u512a\u7570\u7684\u6297\u566a\u80fd\u529b\uff0c\u6210\u70ba\u8907\u96dc\u7db2\u8def\u5206\u6790\u7684\u9996\u9078AI\u5de5\u5177\u3002<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/aicats.wiki\/wp-content\/uploads\/2025\/08\/my_prefix_1754620360.png\" alt=\"\u57fa\u56e0\u7db2\u8def\u5206\u6790\u5de5\u5177\u6bd4\u8f03\u8868\" class=\"wp-image-51824\"\/><figcaption class=\"wp-element-caption\">\u5716\uff0f\u57fa\u56e0\u7db2\u8def\u5206\u6790\u5de5\u5177\u6bd4\u8f03\u8868<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">\u7d50\u8a9e<\/h2>\n\n\n\n<p><strong>Genie3\u6191\u85c9\u8457\u5353\u8d8aAI\u5efa\u6a21\u529b\u3001\u53ef\u9760\u7684\u57fa\u56e0\u8abf\u63a7\u63a8\u8ad6\u3001\u9748\u6d3b\u5951\u5408\u591a\u5834\u666f\u7684\u80fd\u529b\uff0c\u5df2\u6210\u70ba\u5206\u5b50\u751f\u7269\u5b78\u3001\u8f49\u9304\u7d44\u3001\u55ae\u7d30\u80de\u7d44\u5b78\u7814\u7a76\u7684\u5fc5\u5099\u5229\u5668<\/strong>\u3002<\/p>\n\n\n\n<p>\u4e0d\u8ad6\u662f\u75be\u75c5\u6a5f\u5236\u89e3\u6790\u3001\u5408\u6210\u751f\u7269\u8a2d\u8a08\uff0c\u9084\u662f\u751f\u4fe1\u7ba1\u9053\u81ea\u52d5\u5316\uff0cGenie3\u90fd\u70ba\u79d1\u7814\u8cc7\u6599\u6df1\u5ea6\u6316\u6398\u5efa\u7acb\u4e86\u5805\u5be6\u57fa\u790e\u3002\u76ee\u524dGenie3\u8fed\u4ee3\u5feb\u901f\u3001\u793e\u7fa4\u652f\u6301\u8c50\u5bcc\uff0c\u5728\u751f\u547d\u79d1\u5b78AI\u5de5\u4ff1\u751f\u614b\u4e2d\u65e5\u76ca\u91cd\u8981\u3002<strong>\u5c0d\u65bc\u6b32\u9032\u884c\u57fa\u56e0\u8abf\u63a7\u7db2\u8def\u6df1\u5c64\u7814\u7a76\u7684\u79d1\u5b78\u7814\u7a76\u4eba\u54e1\uff0cGenie3\u662f\u503c\u5f97\u4fe1\u8cf4\u7684\u512a\u5148\u5e73\u53f0<\/strong>\u3002<\/p>\n\n\n\n<p><em>\u66f4\u591a\u8a73\u7d30\u6848\u4f8b\u548c\u6578\u64da\u53c3\u898b<a href=\"https:\/\/bioconductor.org\/packages\/release\/bioc\/html\/GENIE3.html\" target=\"_blank\"  rel=\"nofollow noopener\"  class=\"external\" >\u5b98\u65b9\u6587\u6a94<\/a>\u8207\u570b\u969b\u524d\u6cbf\u5b78\u8853\u8ad6\u6587\u3002<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Genie3\u662f\u76ee\u524d\u57fa\u56e0\u8c03\u63a7\u7f51\u7edc\u91cd\u5efa\u9886\u57df\u6700\u53d7\u63a8\u5d07\u7684AI\u5de5\u5177\u4e4b\u4e00\uff0c\u4f9d\u9760\u96c6\u6210\u5b66\u4e60\uff08\u5982\u968f\u673a\u68ee\u6797\uff09\u7b97\u6cd5\uff0c\u80fd\u9ad8\u6548\u6316\u6398\u57fa\u56e0\u95f4 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_crsspst_to_aicatswiki":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[305],"tags":[247,352,906,907],"content_visibility":[262],"class_list":["post-25001","post","type-post","status-publish","format-standard","hentry","category-ai-tools-platforms","tag-ai"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/aicats.wiki\/tw\/wp-json\/wp\/v2\/posts\/25001","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/aicats.wiki\/tw\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/aicats.wiki\/tw\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/aicats.wiki\/tw\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/aicats.wiki\/tw\/wp-json\/wp\/v2\/comments?post=25001"}],"version-history":[{"count":1,"href":"https:\/\/aicats.wiki\/tw\/wp-json\/wp\/v2\/posts\/25001\/revisions"}],"predecessor-version":[{"id":25265,"href":"https:\/\/aicats.wiki\/tw\/wp-json\/wp\/v2\/posts\/25001\/revisions\/25265"}],"wp:attachment":[{"href":"https:\/\/aicats.wiki\/tw\/wp-json\/wp\/v2\/media?parent=25001"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/aicats.wiki\/tw\/wp-json\/wp\/v2\/categories?post=25001"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/aicats.wiki\/tw\/wp-json\/wp\/v2\/tags?post=25001"},{"taxonomy":"content_visibility","embeddable":true,"href":"https:\/\/aicats.wiki\/tw\/wp-json\/wp\/v2\/content_visibility?post=25001"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}